Jack Rees is a brilliant scientist, who is responsible for the creation of a virus that eliminated 80 percent of the world’s population. a survivor of a man-made plague that transforms humans into bloodthirsty mutants. He wanders alone through New York City ground zero where it all started , calling out for other possible survivors, and working on finding a cure for the plague using his own immune blood. Rees knows he is badly outnumbered and that the odds are against him, meanwhile the infected wait for him to make a mistake that will deliver Rees into their hands.